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For this review, we evaluated recommendations from the Japanese Circulation Society / Japanese Heart Failure Society (JCS/JHFS 2025), American Heart Association (AHA 2022), and European Society of Cardiology (ESC 2021/2023), as these represent widely cited, contemporary international guidelines that incorporate the most up-to-date clinical trial evidence and offer complementary perspectives across different healthcare systems
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The technology addresses previous challenges, significantly enhancing drug uniformity, preventing contamination, and ensuring stability
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